SCHEMBL1634950

SCHEMBL1634950

O=C(O)c1c(C(=O)O)c(C(=O)O)c(C(F)(F)F)c(C(F)(F)F)c1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 1/20 0.36
▸ TSHR P16473 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ RXRA P19793 1/20 0.34
▸ RXRB P28702 1/20 0.34
▸ RXRG P48443 1/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ DAO P14920 1/20 0.33
▸ SRD5A2 P31213 1/20 0.33
▸ CA12 O43570 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA7 P43166 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ CA14 Q9ULX7 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ NOTUM Q6P988 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9142308 0.91 GPR35 (0.38) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL436571 0.91 GPR35 (0.38) GPR35TSHRSMN1; SMN2RXRARXRB
Hydrochloric Acid SCHEMBL9344466 0.88 GPR35 (0.36) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL31244452 0.88 GPR35 (0.36) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL1100208 0.87 GPR35 (0.33) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL31542027 0.83 SMN1; SMN2 (0.41) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL14322147 0.81 SMN1; SMN2 (0.39) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL3197716 0.76 THRB (0.37) THRB
SCHEMBL22115216 0.76 SMN1; SMN2 (0.44) GPR35TSHRSMN1; SMN2RXRARXRB
SCHEMBL10606616 0.76 SMN1; SMN2 (0.48) GPR35TSHRSMN1; SMN2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10087284-B2 Fluorine-containing polymerizable monomer and polymer compound using same CENTRAL GLASS COMPANY, LIMITED (JP) 2018-10-02 — — US disclosed
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 — — US disclosed
US-20170088666-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-03-30 — — US disclosed
US-9550711-B2 Fluorine-containing polymerizable monomer and polymer compound using same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-01-24 — — US disclosed
EP-2716351-B1 GAS SEPARATION MEMBRANE CENTRAL GLASS CO LTD (JP) 2016-06-29 — — EP disclosed
US-9061253-B2 Gas separation membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2015-06-23 — — US disclosed
US-9056285-B2 Gas separation membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2015-06-16 — — US disclosed
US-9050566-B2 Gas separation membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2015-06-09 — — US disclosed
US-20140174293-A1 Gas Separation Membrane CENTRAL GLASS COMPANY, LIMITED (JP) 2014-06-26 — — US disclosed
US-20140148548-A1 Fluorine-Containing Polymerizable Monomer And Polymer Compound Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 — — US disclosed
US-20080221298-A1 Fluorinated Diamine and Polymer Made from the Same CENTRAL GLASS COMPANY, LIMITED (JP) 2008-09-11 — — US disclosed
EP-1832618-A1 FLUORINATED DIAMINE AND POLYMER MADE FROM THE SAME Central Glass Company, Limited (JP) 2007-09-12 — — EP disclosed
EP-1810963-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME Central Glass Company, Limited (JP) 2007-07-25 — — EP disclosed
EP-1783158-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME Central Glass Company, Limited (JP) 2007-05-09 — — EP disclosed
CN-1908772-A LCD device FUJI PHOTO FILM CO LTD (JP) 2007-02-07 — — CN disclosed
EP-0659800-B1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS CO LTD (JP) 1999-06-23 — — EP disclosed
US-5840369-A SCREEN PRINTING POLYIMIDE PRECURSOR INK ON SUBSTRATE, REMOVING SOLVENT, THERMALLY CURING INK TO FORM POLYIMIDE RELIEF PATTERN FILM CENTRAL GLASS CO., LTD. (JP) 1998-11-24 — — US disclosed
US-5686525-A THIXOTROPIC SCREEN PRINTING INK COMPRISING A HEAT TREATED POLYAMIC ACID SOLUTION OBTAINED BY REACTION OF AROMATIC TETRACARBOXYLIC ACID, DIAMINE AND A MALEIMIDE; RELIEF IMAGES CENTRAL GLASS COMPANY, LTD. (JP) 1997-11-11 — — US disclosed
US-5478918-A Low stress polyimide composition and precursor composition solution of same CENTRAL GLASS COMPANY, LIMITED (JP) 1995-12-26 — — US disclosed
EP-0659800-A1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS COMPANY, LIMITED (JP) 1995-06-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221298-A1 Fluorinated Diamine and Polymer Made from the Same AFF1, AFF2, SAT1 GPR35 2453/4885TSHR 2583/4885SMN1; SMN2 1235/4885
US-20140148548-A1 Fluorine-Containing Polymerizable Monomer And Polymer Compound Using Same AFF4, AFF2, AFF1 GPR35 1512/4885TSHR 1806/4885SMN1; SMN2 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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