SCHEMBL1635186

SCHEMBL1635186

O=C(O)c1cc(C(F)(F)F)c(C(=O)O)c(C(=O)O)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ASPH Q12797 1/20 0.46
NOTUM Q6P988 3/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CES2 O00748 2/20 0.37
SORT1 Q99523 3/20 0.37
TAS2R14 Q9NYV8 4/20 0.36
CFTR P13569 1/20 0.36
GLRA3 O75311 1/20 0.35
GLRB P48167 1/20 0.35
GRIK1 P39086 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28155006 0.86 ASPH (0.37) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL1098875 0.82 ASPH (0.44) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL29404413 0.82 ASPH (0.44) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL28488951 0.81 GLRA3 (0.39) ASPHNOTUMKDM4EALDH1A1HPGD
Water SCHEMBL25435119 0.80 ASPH (0.43) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL8037311 0.80 CES2 (0.47) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL15920412 0.80 ASPH (0.53) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL3036944 0.80 ASPH (0.59) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL9185655 0.79 ASPH (0.39) ASPHNOTUMKDM4EALDH1A1HPGD
SCHEMBL1100670 0.79 ASPH (0.42) ASPHNOTUMKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730845-A High-fluorine-content biphenyl diamine, colorless polyimide optical film, and preparation method and application thereof 华南理工大学 2023-09-12 CN disclosed
US-10087284-B2 Fluorine-containing polymerizable monomer and polymer compound using same CENTRAL GLASS COMPANY, LIMITED (JP) 2018-10-02 US disclosed
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
CN-104837809-B Diamine containing hexafluoroisopropanol group, polyimide and polyamide using the same, cyclized product thereof, and method for producing the same 中央硝子株式会社 2017-07-07 CN disclosed
US-20170088666-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-03-30 US disclosed
CN-104822445-B Gas separation membrane 中央硝子株式会社 2017-03-15 CN disclosed
CN-104822444-B Gas separation membrane 中央硝子株式会社 2017-03-08 CN disclosed
EP-2716351-B1 GAS SEPARATION MEMBRANE CENTRAL GLASS CO LTD (JP) 2016-06-29 EP disclosed
CN-103561852-B Gas separation membrane CENTRAL GLASS CO.,LTD. (JP) 2016-03-30 CN disclosed
CN-103562261-B Fluoropolymer monomer and use its macromolecular compound CENTRAL GLASS CO.,LTD. (JP) 2016-03-16 CN disclosed
US-20080234460-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same CENTRAL GLASS CO., LTD. (JP) 2008-09-25 US disclosed
US-20080221298-A1 Fluorinated Diamine and Polymer Made from the Same CENTRAL GLASS COMPANY, LIMITED (JP) 2008-09-11 US disclosed
EP-1832618-A1 FLUORINATED DIAMINE AND POLYMER MADE FROM THE SAME Central Glass Company, Limited (JP) 2007-09-12 EP disclosed
EP-1810963-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME Central Glass Company, Limited (JP) 2007-07-25 EP disclosed
EP-1783158-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME Central Glass Company, Limited (JP) 2007-05-09 EP disclosed
EP-0659800-B1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS CO LTD (JP) 1999-06-23 EP disclosed
US-5840369-A SCREEN PRINTING POLYIMIDE PRECURSOR INK ON SUBSTRATE, REMOVING SOLVENT, THERMALLY CURING INK TO FORM POLYIMIDE RELIEF PATTERN FILM CENTRAL GLASS CO., LTD. (JP) 1998-11-24 US disclosed
US-5686525-A THIXOTROPIC SCREEN PRINTING INK COMPRISING A HEAT TREATED POLYAMIC ACID SOLUTION OBTAINED BY REACTION OF AROMATIC TETRACARBOXYLIC ACID, DIAMINE AND A MALEIMIDE; RELIEF IMAGES CENTRAL GLASS COMPANY, LTD. (JP) 1997-11-11 US disclosed
US-5478918-A Low stress polyimide composition and precursor composition solution of same CENTRAL GLASS COMPANY, LIMITED (JP) 1995-12-26 US disclosed
EP-0659800-A1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS COMPANY, LIMITED (JP) 1995-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234460-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same AFF2, FRG1, PFAS ASPH 2196/4885NOTUM 700/4885KDM4E 3487/4885
US-20080221298-A1 Fluorinated Diamine and Polymer Made from the Same AFF1, AFF2, SAT1 ASPH 1994/4885NOTUM 2933/4885KDM4E 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.