SCHEMBL16353029

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16353051	0.94	SLC22A1 (0.38)	SLC22A1DNM1CES2CES1SMN1; SMN2
	SCHEMBL16353033	0.92	DNM1 (0.39)	CYP2C19POLBBLMATMDNM1
	SCHEMBL16353011	0.90	CES1 (0.38)	SLC22A1CYP2C19DNM1CES2CES1
	SCHEMBL16353030	0.87	SLC22A1 (0.38)	SLC22A1DNM1CES2CES1KDM4E
	SCHEMBL16352988	0.86	TDP1 (0.37)	SLC22A1CYP2C19POLBBLMATM
	SCHEMBL16353018	0.82	DNM1 (0.43)	SLC22A1CYP2C19POLBBLMATM
	SCHEMBL16352999	0.81	SLC22A1 (0.39)	SLC22A1DNM1SMN1; SMN2TDP1ACHE
	SCHEMBL570209	0.79	CYP2C19 (0.56)	CYP2C19POLBBLMATMDNM1
	SCHEMBL16352995	0.79	CYP2C19 (0.56)	SLC22A1CYP2C19POLBBLMATM
	SCHEMBL16353061	0.78	SLC22A1 (0.36)	SLC22A1CYP2C19POLBBLMATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.