SCHEMBL1635441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636370	0.96	ALOX5 (0.44)	ALOX5PRKDCPDK2GGPS1PTGES2
	SCHEMBL1636918	0.92	ALOX5 (0.47)	ALOX5PRKDCPDK2GGPS1PTGES2
	SCHEMBL1635703	0.90	ALOX5 (0.41)	ALOX5PRKDCPDK2GGPS1PGR
	SCHEMBL12126819	0.89	ALOX5 (0.39)	ALOX5PRKDCPDK2GGPS1PTGES2
	SCHEMBL1637350	0.88	ALOX5 (0.46)	ALOX5PRKDCPDK2GGPS1PTGES2
	SCHEMBL17057187	0.88	PDK2 (0.42)	ALOX5PRKDCPDK2
	SCHEMBL20276869	0.87	ALOX5 (0.59)	ALOX5PRKDCGGPS1PTGES2PGR
	SCHEMBL18086150	0.86	ALOX5 (0.53)	ALOX5PRKDCPDK2GGPS1PTGES2
	SCHEMBL16017825	0.86	ALOX5 (0.56)	ALOX5PRKDCPDK2GGPS1PTGES2
	SCHEMBL24719177	0.85	ALOX5 (0.40)	ALOX5PRKDCPDK2GGPS1PTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.