SCHEMBL1635703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17057187	0.93	PDK2 (0.42)	ALOX5PDK2PRKDC
	SCHEMBL1637339	0.92	ALOX5 (0.43)	ALOX5PDK2PRKDCGGPS1
	SCHEMBL1635739	0.90	ALOX5 (0.38)	ALOX5PDK2PRKDCPGRPIK3CD
	SCHEMBL1635441	0.90	ALOX5 (0.45)	ALOX5PDK2PRKDCPGRPIK3CD
	SCHEMBL1636370	0.88	ALOX5 (0.44)	ALOX5PDK2PRKDCPIK3CDPIK3CA
	SCHEMBL17640345	0.87	PDK2 (0.37)	ALOX5PDK2PRKDCKDM4EALDH1A1
	SCHEMBL25050942	0.86	ALOX5 (0.51)	ALOX5PRKDCPGRGGPS1CYP2C19
	SCHEMBL17640305	0.86	PDK2 (0.36)	ALOX5PDK2PRKDCKDM4EALDH1A1
	SCHEMBL17640467	0.86	PDK2 (0.36)	ALOX5PDK2PRKDCKDM4EALDH1A1
	SCHEMBL17425720	0.86	PDK2 (0.36)	ALOX5PDK2PRKDCKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.