Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355190 | 0.97 | BACE1 (0.39) | BACE1MAPTAPPGAAAKT1 | |
| SCHEMBL16746566 | 0.90 | BACE1 (0.35) | BACE1MAPTAPPDRD2DRD3 | |
| SCHEMBL16355186 | 0.88 | KDM4E (0.43) | BACE1MAPTAPPGAAKDM4E | |
| SCHEMBL16355187 | 0.88 | KDM4E (0.43) | BACE1MAPTAPPGAAKDM4E | |
| SCHEMBL23816974 | 0.88 | BACE1 (0.33) | BACE1MAPTAPPAKT1AKT2 | |
| SCHEMBL23816986 | 0.88 | BACE1 (0.33) | BACE1MAPTAPPAKT1AKT2 | |
| SCHEMBL29359500 | 0.87 | HSD11B1 (0.37) | GAAAKT1AKT2KDM4EALDH1A1 | |
| SCHEMBL307038 | 0.87 | HSD11B1 (0.37) | GAAAKT1AKT2KDM4EALDH1A1 | |
| SCHEMBL29749791 | 0.87 | HSD11B1 (0.37) | GAAAKT1AKT2KDM4EALDH1A1 | |
| SCHEMBL3101056 | 0.86 | KDM4E (0.39) | BACE1MAPTAPPGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140374677-A1 | COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR | FUJIFILM CORPORATION (JP) | 2014-12-25 | — | — | US | disclosed |
| US-20140374677-A1 | COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR | FUJIFILM CORPORATION (JP) | 2014-12-25 | — | — | US | disclosed |