SCHEMBL16355190

SCHEMBL16355190

CCCOc1ccc(-c2c(-c3ccccc3)nc(-c3ccccc3Cl)n2C2(c3ccccc3Cl)N=C(c3ccccc3)C(c3ccc(OC)cc3)=N2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 0.39
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
APP P05067 2/20 0.35
PIK3CD O00329 1/20 0.35
GAA P10253 2/20 0.34
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16355188 0.97 BACE1 (0.41) BACE1KDM4EALDH1A1MAPTCYP1A2
SCHEMBL16355186 0.92 KDM4E (0.43) BACE1KDM4EALDH1A1LMNANPSR1
SCHEMBL16355187 0.92 KDM4E (0.43) BACE1KDM4EALDH1A1LMNANPSR1
SCHEMBL3101056 0.90 KDM4E (0.39) BACE1KDM4EALDH1A1LMNANPSR1
SCHEMBL30358508 0.90 KDM4E (0.39) BACE1KDM4EALDH1A1LMNANPSR1
SCHEMBL16355189 0.89 ALDH1A1 (0.40) BACE1KDM4EALDH1A1LMNANPSR1
SCHEMBL16746564 0.88 FABP4 (0.43) ALDH1A1LMNAPTGS2
SCHEMBL16746566 0.87 BACE1 (0.35) BACE1MAPTAPPDRD2DRD3
SCHEMBL23816986 0.86 BACE1 (0.33) BACE1TDP1L3MBTL1MAPTAPP
SCHEMBL23816974 0.86 BACE1 (0.33) BACE1TDP1L3MBTL1MAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed