SCHEMBL16355186

SCHEMBL16355186

COc1ccc(-c2c(-c3ccccc3)nc(-c3ccccc3Cl)n2C2(c3ccccc3Cl)N=C(c3ccccc3)C(c3ccccc3)=N2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
HPGD P15428 1/20 0.37
APP P05067 1/20 0.37
BACE1 P56817 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16355187 1.00 KDM4E (0.43) KDM4EALDH1A1LMNANPSR1L3MBTL1
SCHEMBL3101056 0.98 KDM4E (0.39) KDM4EALDH1A1LMNANPSR1L3MBTL1
SCHEMBL30358508 0.98 KDM4E (0.39) KDM4EALDH1A1LMNANPSR1L3MBTL1
SCHEMBL16355189 0.96 ALDH1A1 (0.40) KDM4EALDH1A1LMNANPSR1L3MBTL1
SCHEMBL16355190 0.92 BACE1 (0.39) KDM4EALDH1A1LMNANPSR1L3MBTL1
SCHEMBL16746549 0.91 APP (0.35) KDM4EALDH1A1LMNANPSR1L3MBTL1
SCHEMBL29749791 0.91 HSD11B1 (0.37) KDM4EALDH1A1LMNAL3MBTL1GAA
SCHEMBL29359500 0.91 HSD11B1 (0.37) KDM4EALDH1A1LMNAL3MBTL1GAA
SCHEMBL307038 0.91 HSD11B1 (0.37) KDM4EALDH1A1LMNAL3MBTL1GAA
SCHEMBL17133351 0.90 KDM4E (0.48) KDM4EALDH1A1LMNANPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed