Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.47 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355773 | 0.87 | PRSS1 (0.44) | PRSS1PRSS2PRSS3RXRANR1H2 | |
| SCHEMBL15876023 | 0.81 | S1PR1 (0.51) | ALDH1A1S1PR1PRKXACVR1S1PR5 | |
| SCHEMBL18286872 | 0.77 | PRSS1 (0.48) | PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL16355821 | 0.75 | LTB4R (0.43) | PRSS1PRSS2PRSS3RXRANR1H2 | |
| SCHEMBL13195438 | 0.75 | S1PR1 (0.53) | ALDH1A1S1PR1PRKXACVR1S1PR5 | |
| SCHEMBL16355879 | 0.73 | BCHE (0.42) | PRSS1PRSS2PRSS3ALDH1A1S1PR1 | |
| SCHEMBL15889199 | 0.73 | PRSS1 (0.62) | PRSS1PRSS2PRSS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL16355816 | 0.72 | NR4A2 (0.40) | RXRANR1H2S1PR1PRKXACVR1 | |
| SCHEMBL16355782 | 0.71 | ALDH1A1 (0.45) | ALDH1A1S1PR1PRKXACVR1S1PR5 | |
| SCHEMBL15876231 | 0.71 | FFAR1 (0.62) | S1PR1PRKXACVR1S1PR5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | SERPINB1, REN, SPINT2 | PRSS1 13/4885PRSS2 5/4885PRSS3 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.