Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 17/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16356092 | 1.00 | TMPRSS15 (0.55) | TMPRSS15PRSS1FOLH1PRSS2PRSS3 | |
| SCHEMBL15876110 | 0.91 | TMPRSS15 (0.64) | TMPRSS15PRSS1 | |
| SCHEMBL16356099 | 0.91 | TMPRSS15 (0.64) | TMPRSS15PRSS1 | |
| SCHEMBL15888203 | 0.90 | TMPRSS15 (0.52) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL16356101 | 0.88 | TMPRSS15 (0.50) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL16356104 | 0.88 | TMPRSS15 (0.50) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL11432213 | 0.85 | PRSS1 (0.54) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL16356089 | 0.85 | PRSS1 (0.46) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL16356107 | 0.85 | PRSS1 (0.46) | TMPRSS15PRSS1PRSS2PRSS3 | |
| SCHEMBL11309501 | 0.84 | ALDH1A1 (0.54) | TMPRSS15PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | SERPINB1, REN, SPINT2 | TMPRSS15 4/4885PRSS1 13/4885FOLH1 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.