Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 6/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | SI | P14410 | 6/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470767 | 0.86 | ASAH1 (0.41) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL16357075 | 0.86 | CYP1A2 (0.39) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL8210801 | 0.75 | ASAH1 (0.49) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL22101596 | 0.73 | ASAH1 (0.56) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL14470765 | 0.73 | CYP1A2 (0.38) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL14470768 | 0.71 | ASAH1 (0.40) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL20928041 | 0.70 | ASAH1 (0.53) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL14470772 | 0.70 | ASAH1 (0.41) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL22649182 | 0.69 | ASAH1 (0.51) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL12648519 | 0.69 | FAAH (0.53) | ASAH1KMT2AMAPTFAAHMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |