Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 5/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | SI | P14410 | 5/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470765 | 0.88 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2D6ASAH1ALDH1A1 | |
| SCHEMBL16357074 | 0.86 | ASAH1 (0.43) | ASAH1ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL8220243 | 0.80 | ASAH1 (0.45) | CYP1A2CYP3A4CYP2D6ASAH1ALDH1A1 | |
| SCHEMBL14470767 | 0.73 | ASAH1 (0.41) | ASAH1ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL8218828 | 0.70 | ASAH1 (0.45) | CYP1A2CYP3A4CYP2D6ASAH1ALDH1A1 | |
| SCHEMBL22101596 | 0.69 | ASAH1 (0.56) | ASAH1ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL14470768 | 0.68 | ASAH1 (0.40) | ASAH1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL20928041 | 0.66 | ASAH1 (0.53) | ASAH1ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL22649182 | 0.65 | ASAH1 (0.51) | ASAH1ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL12648519 | 0.65 | FAAH (0.53) | ASAH1ALDH1A1KMT2AMAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |