Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 5/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | SI | P14410 | 5/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16357075 | 0.88 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2D6ASAH1F12 | |
| SCHEMBL14470767 | 0.86 | ASAH1 (0.41) | ASAH1F12ALDH1A1KMT2AMAPT | |
| SCHEMBL14470768 | 0.81 | ASAH1 (0.40) | ASAH1F12KMT2AMAPTTSHR | |
| SCHEMBL8220243 | 0.78 | ASAH1 (0.45) | CYP1A2CYP3A4CYP2D6ASAH1F12 | |
| SCHEMBL20928041 | 0.73 | ASAH1 (0.53) | ASAH1F12ALDH1A1KMT2AMAPT | |
| SCHEMBL16357074 | 0.73 | ASAH1 (0.43) | ASAH1F12ALDH1A1KMT2AMAPT | |
| SCHEMBL14470772 | 0.70 | ASAH1 (0.41) | ASAH1F12ALDH1A1KMT2AMAPT | |
| SCHEMBL8218828 | 0.69 | ASAH1 (0.45) | CYP1A2CYP3A4CYP2D6ASAH1F12 | |
| SCHEMBL14470770 | 0.69 | ASAH1 (0.39) | ASAH1F12KMT2AMAPTTSHR | |
| SCHEMBL22101596 | 0.67 | ASAH1 (0.56) | ASAH1F12ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | MMP12, ADAMTS1, ADAM33 | CYP1A2 2345/4885CYP3A4 3543/4885CYP2D6 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.