Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217853 | 1.00 | NAMPT (0.43) | NAMPTGRM5ADAM17TAS1R3TAS1R1 | |
| SCHEMBL8275482 | 0.87 | ADAM17 (0.38) | ADAM17SCN9AHTR1A | |
| SCHEMBL8217842 | 0.81 | ADAM17 (0.63) | ADAM17 | |
| SCHEMBL8274845 | 0.79 | ADAM17 (0.44) | NAMPTGRM5ADAM17TAS1R3TAS1R1 | |
| SCHEMBL13544574 | 0.79 | NAMPT (0.43) | NAMPTGRM5ADAM17TAS1R3TAS1R1 | |
| SCHEMBL8274427 | 0.79 | ADAM17 (0.37) | ADAM17SCN9A | |
| SCHEMBL8223420 | 0.78 | ADAM17 (0.43) | NAMPTGRM5ADAM17TAS1R3TAS1R1 | |
| SCHEMBL8273353 | 0.77 | ADAM17 (0.61) | NAMPTGRM5ADAM17TAS1R3TAS1R1 | |
| SCHEMBL8274846 | 0.77 | ADAM17 (0.61) | NAMPTGRM5ADAM17TAS1R3TAS1R1 | |
| SCHEMBL8273448 | 0.77 | TSHR (0.40) | SCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |