Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 10/20 | 0.51 |
| ▸ | STARD10 | Q9Y365 | 3/20 | 0.48 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066590 | 0.78 | PCTP (0.79) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL17066575 | 0.76 | PCTP (0.77) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL17066524 | 0.75 | PCTP (0.79) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL17066525 | 0.74 | PCTP (0.78) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL17066522 | 0.73 | PCTP (0.80) | PCTPSTARD10STARD7LMNAPOLB | |
| SCHEMBL12903628 | 0.71 | PCTP (0.77) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL18430479 | 0.70 | PCTP (0.44) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL22554108 | 0.70 | GPR35 (0.42) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL17284883 | 0.69 | PCTP (0.66) | PCTPSTARD10STARD7LMNASMN1; SMN2 | |
| SCHEMBL17066528 | 0.68 | PCTP (0.78) | PCTPSTARD10STARD7LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011022393-A2 | PHOSPHATIDYLCHOLINE TRANSFER PROTEIN INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-02-24 | — | — | WO | disclosed |