Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL1512185 | 0.96 | CA12 (0.52) | CA12CA2CA9ALDH1A1CYP3A4 | |
| Resorcinol SCHEMBL20741439 | 0.92 | PARP1 (0.48) | CA12CA2CA9ALDH1A1CYP3A4 | |
| Metacresol SCHEMBL28088215 | 0.86 | ACHE (0.65) | CA12CA2CA9ALDH1A1CYP3A4 | |
| SCHEMBL9714684 | 0.84 | DRD2 (0.53) | ENPP2CHRM2CHRM1CHRM3 | |
| Glutaral SCHEMBL5181693 | 0.83 | TDP1 (0.55) | CA12CA2CA9CA14HIF1A | |
| SCHEMBL11219508 | 0.82 | MGLL (0.55) | ENPP2CHRM2CHRM1CHRM3 | |
| Glutaral SCHEMBL6482353 | 0.81 | CYP3A4 (0.43) | CA12CA2CA9ALDH1A1CYP3A4 | |
| SCHEMBL21397284 | 0.81 | MGLL (0.58) | CDK1ENPP2CHRM2CHRM1CHRM3 | |
| SCHEMBL9160657 | 0.81 | CCNB2 (0.56) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL28507389 | 0.81 | MGLL (0.58) | CDK1ENPP2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080109086-A1 | Expanding Adhesive Foam Structure to Reduce Stomach Volume | ETHICON ENDO-SURGERY, INC. | 2008-05-08 | — | — | US | claimed |
| EP-1355611-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | Closure Medical Corporation (US) | 2003-10-29 | — | — | EP | claimed |
| US-20020147462-A1 | Bronchial occlusion method and apparatus | CLOSURE MEDICAL CORPORATION | 2002-10-10 | — | — | US | claimed |
| WO-2002022072-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | CLOSURE MEDICAL CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |
| US-5700587-A | BONDING CELLULOSE | BORDEN CHEMICAL, INC. (US) | 1997-12-23 | — | — | US | claimed |
| US-RE47231-E1 | Glue composition for lung volume reduction | PNEUMRX, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-RE46209-E1 | Glue composition for lung volume reduction | PNEUMRX, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140073588-A1 | GLUE COMPOSITION FOR LUNG VOLUME REDUCTION | PNEUMRX, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8431537-B2 | Glue composition for lung volume reduction | PNEUMRX, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20110251136-A1 | GLUE COMPOSITION FOR LUNG VOLUME REDUCTION | PNEUMRX, INC. (US) | 2011-10-13 | — | — | US | disclosed |
| US-7932225-B2 | Glue composition for lung volume reduction | PNEUMRX, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| US-7678767-B2 | Glue compositions for lung volume reduction | PNEUMRX, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20050281739-A1 | Imaging damaged lung tissue using compositions | PNEUMRX, INC. | 2005-12-22 | — | — | US | disclosed |
| US-20050281799-A1 | Targeting damaged lung tissue using compositions | PNEUMRX, INC. | 2005-12-22 | — | — | US | disclosed |
| EP-1355611-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | Closure Medical Corporation (US) | 2003-10-29 | — | — | EP | disclosed |
| US-20020147462-A1 | Bronchial occlusion method and apparatus | CLOSURE MEDICAL CORPORATION | 2002-10-10 | — | — | US | disclosed |
| WO-2002022072-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | CLOSURE MEDICAL CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |
| US-5498647-A | CELLULOSE BOARDS FROM CELLULOSE PARTICLES WITH BINDERS | BORDEN, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| EP-0221959-B1 | REMOVING AND RECOVERING PLANT POLYPHENOLS | MEMTEC LIMITED (AU) | 1990-09-19 | — | — | EP | disclosed |
| WO-1986006589-A1 | REMOVING AND RECOVERING PLANT POLYPHENOLS | MEMTEC LIMITED (AU) | 1986-11-20 | — | — | WO | disclosed |