Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219508 | 0.95 | MGLL (0.55) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL28507389 | 0.93 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL21397284 | 0.93 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL5833923 | 0.93 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL910507 | 0.89 | DRD2 (0.57) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL30882630 | 0.89 | DRD2 (0.57) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL22314080 | 0.86 | CBS (0.53) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| Resorcinol SCHEMBL1635862 | 0.84 | CA12 (0.57) | CHRM2CHRM1CHRM3ENPP2 | |
| SCHEMBL10534002 | 0.82 | OPRK1 (0.54) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL11232474 | 0.82 | DRD2 (0.68) | DRD2DRD1TAAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089216-C | Chewing gum with prolonged and improved flavor containing dipeptide sweetener and method of making same | HOLLAND SWEETENER CO N O F (NL) | 2002-08-21 | — | — | CN | disclosed |
| CN-1230096-A | Chewing gum with extended and improved flavor containing dipeptide sweetener | HOLLAND SWEETENER CO (NL) | 1999-09-29 | — | — | CN | disclosed |
| US-5166210-A | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0397697-A4 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1991-07-03 | — | — | EP | disclosed |
| US-5028615-A | Treatment of hypersensitivity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-07-02 | — | — | US | disclosed |
| EP-0397697-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4?. | RORER INT OVERSEAS (US) | 1990-11-22 | — | — | EP | disclosed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| WO-1989004304-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |