Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16860041 | 0.88 | CYP19A1 (0.33) | PDE3BPDE3AKCNN4KMT2ACYP1A2 | |
| SCHEMBL31332380 | 0.76 | SLC40A1 (0.31) | SMN1; SMN2KMT2ASLC40A1MEN1TDP1 | |
| SCHEMBL16860039 | 0.75 | GRIA2 (0.35) | SMN1; SMN2CA1CA2CA9KCNN4 | |
| SCHEMBL255968 | 0.71 | GPR3 (0.46) | SMN1; SMN2CA1CA2CA9KMT2A | |
| SCHEMBL752924 | 0.71 | DRD2 (0.35) | KMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL21906175 | 0.71 | KEAP1 (0.42) | SMN1; SMN2PDE3BPDE3AKMT2ASLC40A1 | |
| SCHEMBL25769255 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2KMT2ACYP1A2SLC40A1MEN1 | |
| SCHEMBL846187 | 0.69 | GRIA2 (0.37) | SMN1; SMN2CA1CA2CA9KMT2A | |
| SCHEMBL31332197 | 0.69 | NOTUM (0.39) | KMT2AMEN1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL18173654 | 0.68 | GAK (0.31) | SMN1; SMN2KMT2ACYP1A2SLC40A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011059021-A1 | 8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXAMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2011-05-19 | — | — | WO | disclosed |