Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | NPY4R | P50391 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359768 | 0.84 | ECE1 (0.49) | NPY5RNPY4RNPY1RNPY2RBIRC2 | |
| SCHEMBL16359363 | 0.81 | OPRM1 (0.39) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL20951250 | 0.79 | PSMB5 (0.43) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL20951249 | 0.79 | PSMB5 (0.43) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL16306472 | 0.79 | PSMB5 (0.44) | NOD1HPGDSCA12CA1CA9 | |
| SCHEMBL20951291 | 0.77 | NMT2 (0.42) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL20951290 | 0.77 | NMT2 (0.42) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL18862268 | 0.76 | NOD1 (0.43) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL20385911 | 0.76 | NOD1 (0.43) | NPY5RNPY4RNPY1RNPY2RNOD1 | |
| SCHEMBL18857596 | 0.76 | NOD1 (0.43) | NPY5RNPY4RNPY1RNPY2RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |