Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | NPY4R | P50391 | 4/20 | 0.40 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363053 | 0.86 | ECE1 (0.47) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL16359362 | 0.84 | NPY5R (0.39) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL10592847 | 0.84 | NMT1 (0.50) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL7357213 | 0.83 | ECE1 (0.51) | ECE1MMP8MMP2MMP9REN | |
| SCHEMBL7359195 | 0.83 | ECE1 (0.44) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL7360675 | 0.80 | NOD1 (0.55) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL7364998 | 0.79 | PSMB1 (0.43) | ECE1RENBIRC2 | |
| SCHEMBL7366677 | 0.78 | NPY4R (0.43) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL7363492 | 0.77 | NPY4R (0.42) | ECE1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL16359363 | 0.77 | OPRM1 (0.39) | ECE1NPY5RNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |