Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261229 | 0.89 | ADORA2A (0.39) | — | |
| SCHEMBL12261208 | 0.74 | DNPH1 (0.41) | — | |
| SCHEMBL12261152 | 0.73 | ADORA2A (0.47) | PRMT5WDR77ADORA3 | |
| SCHEMBL12261233 | 0.72 | HPRT1 (0.41) | — | |
| SCHEMBL12261182 | 0.70 | PNP (0.40) | — | |
| SCHEMBL12261199 | 0.70 | P2RX1 (0.46) | — | |
| SCHEMBL12261197 | 0.68 | P2RY2 (0.47) | — | |
| SCHEMBL16359865 | 0.67 | HINT1 (0.40) | — | |
| SCHEMBL12261196 | 0.66 | FAP (0.37) | PRMT5WDR77 | |
| SCHEMBL16502723 | 0.63 | PRMT5 (0.35) | PRMT5WDR77ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093608-A1 | CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2010-08-19 | — | — | WO | disclosed |