SCHEMBL1636374

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1635632	0.89	PIM1 (0.42)	ALOX5HSD17B10MAPTHPGDKDM4E
	SCHEMBL22915548	0.86	ALOX5 (0.46)	MCL1ACMSDALOX5HSD17B10MAPT
	SCHEMBL10122355	0.86	ALOX5 (0.46)	MCL1ACMSDALOX5HSD17B10MAPT
	SCHEMBL1635740	0.86	GPR84 (0.40)	ALOX5HSD17B10MAPTHPGDKDM4E
	SCHEMBL24285582	0.86	MCL1 (0.43)	MCL1ACMSDHSD17B10MAPTHPGD
	SCHEMBL10122357	0.84	ALOX5 (0.46)	MCL1ACMSDALOX5HSD17B10MAPT
	SCHEMBL10122630	0.84	ALOX5 (0.44)	MCL1ACMSDALOX5HSD17B10MAPT
	SCHEMBL1637103	0.84	ALOX5 (0.50)	MCL1ACMSDALOX5HSD17B10MAPT
	SCHEMBL10122372	0.84	ALOX5 (0.43)	MCL1ACMSDALOX5HSD17B10MAPT
	SCHEMBL13979514	0.83	MCL1 (0.47)	MCL1ACMSDALOX5HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.