Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23221980 | 0.81 | TSHR (0.32) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL15250900 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13034086 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL14990864 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10352313 | 0.79 | — | — | |
| SCHEMBL16254948 | 0.79 | MAPT (0.32) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2779972 | 0.79 | — | — | |
| SCHEMBL27850723 | 0.77 | MGAM (0.48) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7757259 | 0.76 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL1745 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665362-B1 | OLEFIN CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS INC (US) | 2016-03-30 | — | — | EP | disclosed |
| US-9034897-B2 | Indanyl-substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-C]pyridines, their use as medicament, and pharmaceutical preparations comprising them | SANOFI (FR) | 2015-05-19 | — | — | US | disclosed |
| US-8927719-B2 | Cyanine dyes and their conjugates | LI-COR, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140378686-A1 | Indanyl-Substituted 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridines, Their Use as Medicament, and Pharmaceutical Preparations Comprising Them | SANOFI (FR) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378686-A1 | Indanyl-Substituted 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridines, Their Use as Medicament, and Pharmaceutical Preparations Comprising Them | KCNA1, KCNT1, CACNA1G | MAPT 3464/4885ALDH1A1 256/4885TSHR 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.