Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355715 | 0.85 | SLC7A5 (0.37) | TRPM8MEP1BPRSS1F2OPRM1 | |
| SCHEMBL15876207 | 0.85 | SLC7A5 (0.37) | TRPM8MEP1BPRSS1F2OPRM1 | |
| SCHEMBL15876209 | 0.85 | SLC7A5 (0.37) | TRPM8MEP1BPRSS1F2OPRM1 | |
| SCHEMBL2771473 | 0.81 | CD274 (0.42) | MEP1BPRSS1PPARGF2MEP1A | |
| SCHEMBL2771476 | 0.81 | CD274 (0.42) | MEP1BPRSS1PPARGF2MEP1A | |
| SCHEMBL16366240 | 0.80 | GYS1 (0.39) | TRPM8PPARGGYS1GRIN2DGRIN3B | |
| SCHEMBL15876210 | 0.77 | MEP1B (0.51) | MEP1BMEP1AGYS1 | |
| SCHEMBL2774550 | 0.75 | HDAC3 (0.43) | MEP1BPRSS1PPARGF2GRIN2D | |
| SCHEMBL2774547 | 0.75 | HDAC3 (0.43) | MEP1BPRSS1PPARGF2GRIN2D | |
| SCHEMBL2810622 | 0.75 | HDAC3 (0.43) | MEP1BPRSS1PPARGF2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | SERPINB1, REN, SPINT2 | TRPM8 2856/4885MEP1B 412/4885PRSS1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.