Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 5/20 | 0.56 |
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | OGT | O15294 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991734 | 0.74 | IDO1 (0.54) | IDO1ALDH1A1TP53HSD17B10HPGD | |
| SCHEMBL10987080 | 0.73 | TDP1 (0.55) | IDO1ALDH1A1TP53HSD17B10HPGD | |
| SCHEMBL2978251 | 0.73 | PIK3CB (0.58) | IDO1TP53HSD17B10HPGDPIK3CB | |
| SCHEMBL4414360 | 0.72 | HPGD (0.64) | IDO1TP53HSD17B10HPGDPIK3CB | |
| SCHEMBL23815651 | 0.71 | IDO1 (0.77) | ASAH1IDO1ALDH1A1TP53KMT2A | |
| SCHEMBL5536572 | 0.70 | PKM (0.59) | ALDH1A1HSD17B10HPGDMAPK1PIK3CB | |
| SCHEMBL4997130 | 0.70 | IDO1 (0.45) | ASAH1IDO1ALDH1A1TP53HSD17B10 | |
| SCHEMBL14044191 | 0.70 | LMNA (0.59) | IDO1ALDH1A1TP53HSD17B10HPGD | |
| SCHEMBL5208539 | 0.70 | ASAH1 (0.52) | ASAH1ALDH1A1TP53HSD17B10KMT2A | |
| SCHEMBL3028907 | 0.70 | PIK3CB (0.55) | IDO1ALDH1A1TP53HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
| WO-2014204859-A2 | BCL6 INHIBITORS AS ANTICANCER AGENTS | MELNICK ARI (US) | 2014-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | BCL6, BCL6B, BAZ2A | ASAH1 4774/4885IDO1 1644/4885ALDH1A1 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.