Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353976 | 0.82 | MAOB (0.65) | MAPTMAOBMAOALIPGEPHX1 | |
| SCHEMBL4396712 | 0.79 | MAOA (0.64) | L3MBTL1DYRK1AALDH1A1NPC1MAPK1 | |
| SCHEMBL23290595 | 0.77 | KDM4E (0.43) | L3MBTL1DNMT3ADYRK1AALDH1A1NPC1 | |
| SCHEMBL8735045 | 0.77 | MAPT (0.54) | ALDH1A1NPC1MAPTMAPK1RAB9A | |
| SCHEMBL23290993 | 0.77 | DPP4 (0.41) | L3MBTL1DNMT3ADYRK1AALDH1A1NPC1 | |
| SCHEMBL21819943 | 0.76 | MAOB (0.47) | DYRK1AMAOB | |
| SCHEMBL545073 | 0.75 | DYRK1A (0.49) | L3MBTL1DYRK1ANPC1RAB9AMAOB | |
| SCHEMBL13281549 | 0.75 | RAB9A (0.56) | PIK3CANPC1MAPTRAB9AGPR119 | |
| Bromide SCHEMBL9774868 | 0.74 | SMN1; SMN2 (0.57) | L3MBTL1ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL27712805 | 0.72 | DYRK2 (0.54) | L3MBTL1DYRK1AALDH1A1PIK3CANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011582-A1 | Carboxamide Compounds and Methods for Using the Same | MIDCAP FINANCIAL TRUST | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011582-A1 | Carboxamide Compounds and Methods for Using the Same | PC, AK2, PRKAA2 | L3MBTL1 2576/4885DNMT3A 2017/4885DYRK1A 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.