SCHEMBL1636828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636936	1.00	ESR1 (0.47)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL1636939	0.98	ESR1 (0.46)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL1636944	0.98	ESR1 (0.50)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL13979519	0.96	ESR1 (0.50)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL12037403	0.96	ESR1 (0.50)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL1637404	0.95	HSD17B1 (0.49)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL1636395	0.94	ESR1 (0.46)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL1636030	0.94	ESR1 (0.46)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL12024529	0.94	ESR1 (0.48)	ESR1ESR2ALOX5HSD17B1HSD17B2
	SCHEMBL12024491	0.94	ESR1 (0.48)	ESR1ESR2ALOX5HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.