SCHEMBL1637404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636397	0.95	HSD17B1 (0.47)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL1636936	0.95	ESR1 (0.47)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL1636828	0.95	ESR1 (0.47)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL1636939	0.93	ESR1 (0.46)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL1636944	0.93	ESR1 (0.50)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL25052927	0.91	PLA2G2A (0.44)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL25052920	0.91	PLA2G2A (0.44)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL12037403	0.91	ESR1 (0.50)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL13979519	0.91	ESR1 (0.50)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A
	SCHEMBL17932132	0.90	PLA2G2A (0.43)	HSD17B1HSD17B2PGRPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.