Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637555 | 1.00 | HTR2C (0.56) | HTR2CEEDMEN1KMT2AHTR2A | |
| SCHEMBL1637389 | 1.00 | HTR2C (0.56) | HTR2CEEDMEN1KMT2AHTR2A | |
| SCHEMBL12536768 | 0.84 | HTR2C (0.60) | HTR2CEEDMEN1KMT2AKDM4E | |
| SCHEMBL3957254 | 0.83 | ADRB1 (0.40) | HTR2CEEDMEN1KMT2AHTR2A | |
| SCHEMBL1639240 | 0.83 | ADRB1 (0.40) | HTR2CEEDMEN1KMT2AHTR2A | |
| SCHEMBL1638815 | 0.83 | MAOA (0.43) | HTR2CMEN1KMT2AHTR2AHTR2B | |
| SCHEMBL5562690 | 0.80 | MAOA (0.53) | HTR2CMEN1KMT2AHTR2AHTR2B | |
| SCHEMBL1639545 | 0.80 | MAOA (0.53) | HTR2CMEN1KMT2AHTR2AHTR2B | |
| SCHEMBL6178879 | 0.79 | MEN1 (0.61) | HTR2CEEDMEN1KMT2AHTR2A | |
| SCHEMBL2808985 | 0.79 | MEN1 (0.61) | HTR2CEEDMEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164807-A | Polyurethane-polyurea water dispersion and preparation method thereof | 万华化学集团股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | claimed |
| US-20240052090-A1 | A TWO-COMPONENT POLYURETHANE COMPOSITION, PROCESS FOR PREPARING THE SAME AND A METHOD OF USE THEREOF | ARKEMA FRANCE (FR) | 2024-02-15 | — | — | US | disclosed |
| CN-117279972-A | Two-component polyurethane compositions, methods of making, and methods of using the same | 阿科玛法国 | 2023-12-22 | — | — | CN | disclosed |
| CN-117164807-A | Polyurethane-polyurea water dispersion and preparation method thereof | 万华化学集团股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-4263209-A1 | A TWO-COMPONENT POLYURETHANE COMPOSITION, PROCESS FOR PREPARING THE SAME AND A METHOD OF USE THEREOF | ARKEMA FRANCE (FR) | 2023-10-25 | — | — | EP | disclosed |
| US-11414764-B2 | Method of inhibiting metal corrosion with a piperazine-based polyurea | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-08-16 | — | — | US | disclosed |
| WO-2022133025-A1 | A TWO-COMPONENT POLYURETHANE COMPOSITION, PROCESS FOR PREPARING THE SAME AND A METHOD OF USE THEREOF | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2022-06-23 | — | — | WO | disclosed |
| US-20210115570-A1 | METHOD OF INHIBITING METAL CORROSION WITH A PIPERAZINE-BASED POLYUREA | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2021-04-22 | — | — | US | disclosed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| WO-2008006372-A1 | (3-ARYL-PIPERAZIN-1-YL), (2-ARYL-MORPHOLIN-4-YL) AND (2-ARYL- THIOMORPHOLIN-4-YL) DERIVATIVES OF 6,7-DIALKOXYQUINAZOLINE, 6,7- DIALKOXYPHTALAZINE AND 6,7-DIALKOXYISOQUINOLINE | H. LUNDBECK A/S (DK) | 2008-01-17 | — | — | WO | disclosed |
| EP-1492794-B1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES AND THEIR USE AS DOPAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | LILLY CO ELI (US) | 2007-12-12 | — | — | EP | disclosed |
| US-7214673-B2 | For therapy of psychosis and bipolar disorder | ELI LILLY AND COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-20050203296-A1 | For therapy of psychosis and bipolar disorder | ELI LILLY AND COMPANY | 2005-09-15 | — | — | US | disclosed |
| EP-1492794-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES AND THEIR USE AS DOPAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | ELI LILLY AND COMPANY (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082877-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES AND THEIR USE AS DOPAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | ELI LILLY AND COMPANY (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203296-A1 | For therapy of psychosis and bipolar disorder | DRD4, AFF4, DRD2 | HTR2C 137/4885EED 1421/4885MEN1 4508/4885 |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | P2RX7, P2RX1, P2RX2 | HTR2C 232/4885EED 4592/4885MEN1 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.