Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359921 | 0.84 | TRPA1 (0.39) | TRPA1ATMCYP1A2MAPTCYP2A6 | |
| SCHEMBL1395168 | 0.82 | TSHR (0.41) | CYP1A2CYP2A6TDP1TSHRSMN1; SMN2 | |
| SCHEMBL10616553 | 0.78 | TRPA1 (0.34) | TRPA1ATMCYP1A2MAPTCYP2A6 | |
| SCHEMBL20535490 | 0.78 | TRPA1 (0.34) | TRPA1ATMCYP1A2MAPTALDH1A1 | |
| SCHEMBL986311 | 0.77 | TRPA1 (0.44) | TRPA1ATMCYP1A2MAPTCYP2A6 | |
| SCHEMBL9359930 | 0.73 | TRPA1 (0.46) | TRPA1ATMCYP1A2MAPTCYP2A6 | |
| SCHEMBL1317885 | 0.73 | TRPA1 (0.41) | TRPA1ATMCYP1A2MAPTCYP2A6 | |
| SCHEMBL1313855 | 0.73 | TRPA1 (0.41) | TRPA1ATMCYP1A2MAPTCYP2A6 | |
| SCHEMBL9363790 | 0.72 | TRPA1 (0.31) | TRPA1ATM | |
| SCHEMBL7778415 | 0.72 | TRPA1 (0.44) | TRPA1ATMCYP1A2MAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182161-A1 | METHOD TO IMPROVE WETTABILITY BY REDUCING LIQUID POLYMER MACROMOLECULE MOBILITY THROUGH FORMING POLYMER BLEND SYSTEM | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-07-16 | — | — | US | claimed |
| US-7932342-B2 | Method to improve wettability by reducing liquid polymer macromolecule mobility through forming polymer blend system | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090182161-A1 | METHOD TO IMPROVE WETTABILITY BY REDUCING LIQUID POLYMER MACROMOLECULE MOBILITY THROUGH FORMING POLYMER BLEND SYSTEM | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182161-A1 | METHOD TO IMPROVE WETTABILITY BY REDUCING LIQUID POLYMER MACROMOLECULE MOBILITY THROUGH FORMING POLYMER BLEND SYSTEM | VCL, PCNA, MMP26 | TRPA1 3964/4885ATM 1723/4885CYP1A2 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.