Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315326 | 0.84 | TSHR (0.36) | GAAMAPTALDH1A1ELANEMEN1 | |
| SCHEMBL987485 | 0.82 | TRPA1 (0.35) | TRPA1ATMGAAMAPTALDH1A1 | |
| SCHEMBL28236979 | 0.82 | TRPA1 (0.35) | TRPA1ATMGAAMAPTALDH1A1 | |
| SCHEMBL9359921 | 0.79 | TRPA1 (0.39) | TRPA1ATMGAAMAPTALDH1A1 | |
| SCHEMBL2961136 | 0.79 | ALDH1A1 (0.32) | ALDH1A1ELANEKDM4ENPC1RAB9A | |
| SCHEMBL1636890 | 0.78 | TRPA1 (0.38) | TRPA1ATMGAAMAPTALDH1A1 | |
| SCHEMBL10616553 | 0.73 | TRPA1 (0.34) | TRPA1ATMMAPTCYP1A2 | |
| SCHEMBL1315148 | 0.72 | TSHR (0.36) | GAAMAPTALDH1A1ELANEMEN1 | |
| SCHEMBL986311 | 0.72 | TRPA1 (0.44) | TRPA1ATMMAPTALDH1A1CYP1A2 | |
| SCHEMBL16487294 | 0.72 | HPGD (0.39) | ALDH1A1ELANECYP2D6S1PR1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520434-B | Method for preparing arylalkoxysilanes by dehydrogenative silylation | 美国陶氏有机硅公司 | 2022-08-23 | — | — | CN | claimed |
| EP-3609900-B1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2021-02-17 | — | — | EP | claimed |
| US-20200123181-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2020-04-23 | — | — | US | claimed |
| EP-3609900-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | Dow Silicones Corporation (US) | 2020-02-19 | — | — | EP | claimed |
| WO-2018190999-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORPORATION (US) | 2018-10-18 | — | — | WO | claimed |
| CN-110520434-B | Method for preparing arylalkoxysilanes by dehydrogenative silylation | 美国陶氏有机硅公司 | 2022-08-23 | — | — | CN | disclosed |
| EP-3609900-B1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20200123181-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2020-04-23 | — | — | US | disclosed |
| EP-3609900-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | Dow Silicones Corporation (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018190999-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORPORATION (US) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123181-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DHPS, ALK, BCR | TRPA1 1533/4885ATM 3703/4885GAA 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.