N-Methyl-D-Aspartic Acid (Nmda)

N-Methyl-D-Aspartic Acid (Nmda)

SCHEMBL163692

CN[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MME P08473 4/20 0.40
GNPAT O15228 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
FOLH1 Q04609 1/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
PTGS2 P35354 1/20 0.38
THPO P40225 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL18528187 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL2220 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL19741548 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL167682 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL11297426 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL6954583 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL27949540 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL10763594 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL28052876 0.95 CA2 (0.42) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL431199 0.91 GLRA1 (0.43) CA2CA4TDP1SMN1; SMN2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2808 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746912-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES Simris Biologics GmbH (DE) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4727654-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
EP-4727655-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
EP-4720086-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP claimed
EP-4720087-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP claimed
EP-3570864-B1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-02-18 EP claimed
EP-4218790-B1 MODULATORS OF COMPLEMENT ACTIVITY UCB HOLDINGS INC (US) 2026-02-18 EP claimed
EP-4663654-A1 POLYPEPTIDE AND DERIVATIVE THEREOF, COMPOSITION, AND USE THEREOF Hangzhou Sciwind Biosciences Co., Ltd. (CN) 2025-12-17 EP claimed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US claimed
WO-2005073164-A1 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2005-08-11 WO claimed
US-20040248911-A1 7H-pyrrolo[2,3-d]pyrimidine derivatives BOLD GUIDO (CH) 2004-12-09 US claimed
US-20020155962-A1 Nonaqueous hair styling composition and method of use ANDREW JERGENS COMPANY, THE 2002-10-24 US claimed
EP-0711156-A4 USE OF N-METHYL-ASPARTIC ACID FOR ENHANCING GROWTH AND ALTERING BODY COMPOSITION UNIV MARYLAND (US) 1998-03-04 EP claimed
US-5691377-A ACTIVATE GROWTH HORMONE SECRETION UNIVERSITY OF MARYLAND EASTERN SHORE AND UNIVERSITY OF MARYLAND COLLEGE PARK (US) 1997-11-25 US claimed
EP-0711156-A1 USE OF N-METHYL-ASPARTIC ACID FOR ENHANCING GROWTH AND ALTERING BODY COMPOSITION UNIVERSITY OF MARYLAND AT COLLEGE PARK AND UNIVERSITY OF MARYLAND EASTERN SHORE (US) 1996-05-15 EP claimed
WO-1995003793-A1 USE OF N-METHYL-ASPARTIC ACID FOR ENHANCING GROWTH AND ALTERING BODY COMPOSITION UNIVERSITY OF MARYLAND AT COLLEGE PARK AND UNIVERSITY OF MARYLAND EASTERN SHORE (US) 1995-02-09 WO claimed
EP-0324595-B1 Amino-functional compounds as builders/dispersants in detergent compositions PROCTER & GAMBLE (US) 1995-01-11 EP claimed
US-5221711-A Reacting maleic anhydride with alcohols to form halt-esters, reacting product with certain amines THE PROCTER & GAMBLE COMPANY (US) 1993-06-22 US claimed
EP-0324595-A2 Amino-functional compounds as builders/dispersants in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1989-07-19 EP claimed