N-Methyl-D-Aspartic Acid (Nmda)

N-Methyl-D-Aspartic Acid (Nmda)

SCHEMBL19741548

CNC(CC(=O)O)C(=O)O.CNC(CC(=O)O)C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MME P08473 4/20 0.40
GNPAT O15228 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
FOLH1 Q04609 1/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
PTGS2 P35354 1/20 0.38
THPO P40225 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL18528187 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL2220 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL167682 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL163692 1.00 CA2 (0.45) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL11297426 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL6954583 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL27949540 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL10763594 0.97 CA2 (0.44) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL28052876 0.95 CA2 (0.42) CA2CA4TDP1SMN1; SMN2MME
N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL431199 0.91 GLRA1 (0.43) CA2CA4TDP1SMN1; SMN2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10869955-B2 Joint fat pad formulations, and methods of use thereof ALLERGAN, INC. (US) 2020-12-22 US disclosed
US-20170368236-A1 JOINT FAT PAD FORMULATIONS, AND METHODS OF USE THEREOF ALLERGAN INC (US) 2017-12-28 US disclosed