Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL19741548 | 0.95 | CA2 (0.45) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL2220 | 0.95 | CA2 (0.45) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL163692 | 0.95 | CA2 (0.45) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL167682 | 0.95 | CA2 (0.45) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL18528187 | 0.95 | CA2 (0.45) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL6954583 | 0.93 | CA2 (0.44) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL27949540 | 0.93 | CA2 (0.44) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL11297426 | 0.93 | CA2 (0.44) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL10763594 | 0.93 | CA2 (0.44) | CA2CA4TDP1SMN1; SMN2MME | |
| N-Methyl-D-Aspartic Acid (Nmda) SCHEMBL431199 | 0.86 | GLRA1 (0.43) | CA2CA4TDP1SMN1; SMN2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473135-A | D-METHADONE FOR THE TREATMENT OF PSYCHIATRIC SYMPTOMS | RELMADA THERAPEUTICS INC | 2016-04-06 | — | — | CN | disclosed |