Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 13/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799665 | 1.00 | AKT1 (0.40) | AKT1GRIA4FPR1FPR2IDO1 | |
| SCHEMBL16372224 | 0.85 | GRM5 (0.51) | AKT1FPR1FPR2 | |
| SCHEMBL17799641 | 0.85 | GRM5 (0.51) | AKT1FPR1FPR2 | |
| SCHEMBL17799647 | 0.83 | GRM5 (0.40) | — | |
| SCHEMBL16371880 | 0.83 | GRM5 (0.40) | — | |
| SCHEMBL16371875 | 0.83 | P2RX7 (0.47) | AKT1GRIA4FPR1FPR2 | |
| SCHEMBL17799694 | 0.83 | P2RX7 (0.47) | AKT1GRIA4FPR1FPR2 | |
| SCHEMBL17799744 | 0.82 | TLR7 (0.40) | AKT1FPR1FPR2 | |
| SCHEMBL17799721 | 0.81 | HCRTR1 (0.47) | AKT1FPR1FPR2 | |
| SCHEMBL17799629 | 0.80 | HCRTR1 (0.52) | AKT1FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | Syngenta Participations AG (CH) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015003951-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-15 | — | — | WO | disclosed |