Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634854 | 0.76 | MAPK1 (0.34) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL9198854 | 0.72 | CYP3A4 (0.36) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL5634756 | 0.72 | CYP3A4 (0.36) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL9192901 | 0.71 | LMNA (0.35) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL1074852 | 0.71 | LMNA (0.49) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL6686807 | 0.69 | ERN1 (0.51) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL16391486 | 0.69 | LMNA (0.33) | LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL27563751 | 0.68 | ERN1 (0.35) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL597800 | 0.67 | LMNA (0.45) | ERN1LMNAMAPK1RAB9ACYP3A4 | |
| SCHEMBL5691950 | 0.67 | CYP3A4 (0.42) | SMN1; SMN2LMNAMAPK1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015006615-A1 | ANTICANCER AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-01-15 | — | — | WO | disclosed |