SCHEMBL5634756

SCHEMBL5634756

C=CCOC(=O)N1C=CCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
CHRM1 P11229 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 3/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
FAAH O00519 3/20 0.31
ERN1 O75460 2/20 0.31
MGLL Q99685 1/20 0.31
GPR119 Q8TDV5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5634854 0.90 MAPK1 (0.34) CYP3A4MAPK1LMNARAB9ACHRM1
SCHEMBL9198854 0.76 CYP3A4 (0.36) CYP3A4MAPK1LMNARAB9ACHRM1
SCHEMBL9192901 0.75 LMNA (0.35) CYP3A4MAPK1LMNARAB9ACHRM1
SCHEMBL16391486 0.72 LMNA (0.33) CYP3A4MAPK1LMNARAB9A
SCHEMBL21664601 0.72 CYP1A2 (0.40) LMNACHRM1TSHRPOLB
SCHEMBL16372005 0.72 SMN1; SMN2 (0.43) CYP3A4MAPK1LMNARAB9ACHRM1
SCHEMBL2985134 0.71 LMNA (0.46) CYP3A4MAPK1LMNARAB9ACHRM1
SCHEMBL6754852 0.71 SMN1; SMN2 (0.47) CYP3A4MAPK1LMNARAB9ATSHR
SCHEMBL2839456 0.71 LMNA (0.35) CYP3A4MAPK1LMNARAB9ACHRM1
SCHEMBL8924794 0.71 LMNA (0.42) CYP3A4MAPK1LMNARAB9ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240222705-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY ZHANGJIAGANG GUOTAI-HUARONG NEW CHEMICAL MATERIALS CO., LTD. (CN) 2024-07-04 US claimed
EP-4391135-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY Zhangjiagang Guotai-Huarong New Chemical Materials Co., Ltd (CN) 2024-06-26 EP claimed
CN-115911544-B Nonaqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2024-03-01 CN claimed
CN-115911544-A Non-aqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2023-04-04 CN claimed
WO-2023020314-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY 张家港市国泰华荣化工新材料有限公司 2023-02-23 WO claimed
US-20240222705-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY ZHANGJIAGANG GUOTAI-HUARONG NEW CHEMICAL MATERIALS CO., LTD. (CN) 2024-07-04 US disclosed
US-20240222705-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY ZHANGJIAGANG GUOTAI-HUARONG NEW CHEMICAL MATERIALS CO., LTD. (CN) 2024-07-04 US disclosed
US-20240222705-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY ZHANGJIAGANG GUOTAI-HUARONG NEW CHEMICAL MATERIALS CO., LTD. (CN) 2024-07-04 US disclosed
EP-4391135-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY Zhangjiagang Guotai-Huarong New Chemical Materials Co., Ltd (CN) 2024-06-26 EP disclosed
EP-4391135-A1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM BATTERY Zhangjiagang Guotai-Huarong New Chemical Materials Co., Ltd (CN) 2024-06-26 EP disclosed
CN-115911544-B Nonaqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2024-03-01 CN disclosed
CN-115911544-A Non-aqueous electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2023-04-04 CN disclosed
WO-2013149996-A9 SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS ALMIRALL, S.A. (ES) 2014-02-20 WO disclosed
WO-2013149996-A1 SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS ALMIRALL, S.A. (ES) 2013-10-10 WO disclosed
US-20070161619-A1 Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof ASTRAZENECA AB (SE) 2007-07-12 US disclosed
US-20070161619-A1 Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof ASTRAZENECA AB (SE) 2007-07-12 US disclosed
US-20070161619-A1 Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof ASTRAZENECA AB (SE) 2007-07-12 US disclosed
CN-1946721-A Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof ASTRAZENECA AB (SE) 2007-04-11 CN disclosed
EP-1716146-A1 PYRROLOQUINOLINE AND PIPERIDOQUINOLINE DERIVATIVES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USES THEREOF AstraZeneca AB (SE) 2006-11-02 EP disclosed
WO-2005075476-A1 PYRROLOQUINOLINE AND PIPERIDOQUINOLINE DERIVATIVES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USES THEREOF ASTRAZENECA AB (SE) 2005-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161619-A1 Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof OPRL1, OPRD1, OPRK1 CYP3A4 316/4885MAPK1 3729/4885LMNA 3122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.