Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | PPIA | P62937 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799637 | 1.00 | GRM5 (0.47) | GRM5SMN1; SMN2TDP1KCNMA1FPR1 | |
| SCHEMBL17799705 | 0.86 | NPC1 (0.47) | FPR1FPR2ALDH1A1RAB9AF10 | |
| SCHEMBL16392343 | 0.85 | L3MBTL1 (0.46) | FPR1FPR2MGLLGAAMEN1 | |
| SCHEMBL15294774 | 0.85 | L3MBTL1 (0.46) | FPR1FPR2MGLLGAAMEN1 | |
| SCHEMBL15291806 | 0.85 | L3MBTL1 (0.46) | FPR1FPR2MGLLGAAMEN1 | |
| SCHEMBL17799762 | 0.84 | SIGMAR1 (0.48) | TDP1FPR1FPR2MGLLMEN1 | |
| SCHEMBL17799699 | 0.84 | NPC1 (0.51) | SMN1; SMN2KCNMA1FPR1FPR2RAB9A | |
| SCHEMBL16372277 | 0.84 | SIGMAR1 (0.48) | TDP1FPR1FPR2MGLLMEN1 | |
| SCHEMBL16371986 | 0.84 | NPC1 (0.51) | SMN1; SMN2KCNMA1FPR1FPR2RAB9A | |
| SCHEMBL17799635 | 0.84 | L3MBTL1 (0.46) | SMN1; SMN2FPR1FPR2MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | Syngenta Participations AG (CH) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015003951-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-15 | — | — | WO | disclosed |