SCHEMBL17799762

SCHEMBL17799762

O=C(N[C@H]1CC[C@H]1c1ccc(Cl)cc1)c1ccccc1I

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 1/20 0.48
▸ FPR1 P21462 5/20 0.43
▸ FPR2 P25090 4/20 0.43
▸ FAAH O00519 1/20 0.43
▸ MGLL Q99685 1/20 0.43
▸ CNR1 P21554 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ DRD4 P21917 1/20 0.39
▸ EPHX2 P34913 1/20 0.39
▸ TAS1R3 Q7RTX0 1/20 0.39
▸ TAS1R1 Q7RTX1 1/20 0.39
▸ TAS1R2 Q8TE23 1/20 0.39
▸ GRIA4 P48058 1/20 0.38
▸ HCRTR2 O43614 1/20 0.38
▸ CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16372277 1.00 SIGMAR1 (0.48) SIGMAR1FPR1FPR2FAAHMGLL
SCHEMBL17799705 0.86 NPC1 (0.47) FPR1FPR2MEN1KMT2A
SCHEMBL17799635 0.84 L3MBTL1 (0.46) FPR1FPR2MGLLCNR1MEN1
SCHEMBL17799699 0.84 NPC1 (0.51) FPR1FPR2MEN1KMT2ATAS1R3
SCHEMBL17799637 0.84 GRM5 (0.47) FPR1FPR2MGLLMEN1KMT2A
SCHEMBL16371986 0.84 NPC1 (0.51) FPR1FPR2MEN1KMT2ATAS1R3
SCHEMBL16372272 0.84 GRM5 (0.47) FPR1FPR2MGLLMEN1KMT2A
SCHEMBL17799749 0.83 SIGMAR1 (0.45) SIGMAR1FAAHMGLLDRD4TAS1R3
SCHEMBL16372239 0.83 SIGMAR1 (0.45) SIGMAR1FAAHMGLLDRD4TAS1R3
SCHEMBL17799750 0.81 LMNA (0.54) MGLLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 — — US disclosed
EP-3019476-B1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-01-17 — — EP disclosed
US-9867371-B2 4-membered ring carboxamides used as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2018-01-16 — — US disclosed
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2016-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES TUBA3C, DDT, CYCS SIGMAR1 916/4885FPR1 605/4885FPR2 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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