Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | FPR1 | P21462 | 5/20 | 0.43 |
| ▸ | FPR2 | P25090 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799762 | 1.00 | SIGMAR1 (0.48) | SIGMAR1FPR1FPR2FAAHMGLL | |
| SCHEMBL17799705 | 0.86 | NPC1 (0.47) | FPR1FPR2MEN1KMT2A | |
| SCHEMBL17799635 | 0.84 | L3MBTL1 (0.46) | FPR1FPR2MGLLCNR1MEN1 | |
| SCHEMBL17799699 | 0.84 | NPC1 (0.51) | FPR1FPR2MEN1KMT2ATAS1R3 | |
| SCHEMBL17799637 | 0.84 | GRM5 (0.47) | FPR1FPR2MGLLMEN1KMT2A | |
| SCHEMBL16371986 | 0.84 | NPC1 (0.51) | FPR1FPR2MEN1KMT2ATAS1R3 | |
| SCHEMBL16372272 | 0.84 | GRM5 (0.47) | FPR1FPR2MGLLMEN1KMT2A | |
| SCHEMBL17799749 | 0.83 | SIGMAR1 (0.45) | SIGMAR1FAAHMGLLDRD4TAS1R3 | |
| SCHEMBL16372239 | 0.83 | SIGMAR1 (0.45) | SIGMAR1FAAHMGLLDRD4TAS1R3 | |
| SCHEMBL17799750 | 0.81 | LMNA (0.54) | MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | Syngenta Participations AG (CH) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015003951-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-15 | — | — | WO | disclosed |