SCHEMBL1637385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636216	0.95	ALOX5 (0.47)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL19651715	0.87	ALOX5 (0.58)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL17931957	0.86	ALOX5 (0.44)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL1635355	0.86	ALOX5 (0.46)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL26750776	0.85	ALOX5 (0.61)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL20334566	0.85	ALOX5 (0.40)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL9890263	0.84	ALOX5 (0.38)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL431460	0.84	PIK3CD (0.47)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL25775081	0.84	MAOA (0.55)	ALOX5MAOAMAOBALDH1A1MAPT
	SCHEMBL25775078	0.84	MAOA (0.58)	ALOX5MAOAMAOBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.