Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KIFC1 | Q9BW19 | 8/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.40 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.40 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.40 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295661 | 0.88 | L3MBTL1 (0.48) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL22384053 | 0.88 | L3MBTL1 (0.46) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL16305641 | 0.88 | L3MBTL1 (0.46) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL16295659 | 0.88 | L3MBTL1 (0.48) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL16305638 | 0.87 | L3MBTL1 (0.46) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL22384055 | 0.83 | L3MBTL1 (0.42) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL22384056 | 0.82 | L3MBTL1 (0.41) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL16305639 | 0.82 | L3MBTL1 (0.41) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 | |
| SCHEMBL22384060 | 0.81 | L3MBTL1 (0.45) | L3MBTL1KIFC1CTSSCTSKCTSB | |
| SCHEMBL22384200 | 0.81 | CTSS (0.42) | L3MBTL1KIFC1ADCY6ADCY3ADCY9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-11-02 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| US-9598430-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-08-11 | — | — | US | disclosed |
| US-20160214993-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-07-28 | — | — | US | disclosed |
| US-20150011527-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | L3MBTL1 771/4885KIFC1 4738/4885ADCY6 323/4885 |
| US-20170313717-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | L3MBTL1 771/4885KIFC1 4738/4885ADCY6 323/4885 |
| US-20160214993-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | L3MBTL1 771/4885KIFC1 4738/4885ADCY6 323/4885 |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | L3MBTL1 771/4885KIFC1 4738/4885ADCY6 323/4885 |
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | L3MBTL1 579/4885KIFC1 4749/4885ADCY6 411/4885 |
| US-20150011527-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | L3MBTL1 771/4885KIFC1 4738/4885ADCY6 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.