SCHEMBL1637580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637583	0.97	PLA2G2A (0.40)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL9890223	0.94	KDM4E (0.41)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL16639228	0.92	PLA2G2A (0.46)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL12158880	0.92	PLA2G2A (0.46)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL12158843	0.92	PLA2G2A (0.46)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL9889867	0.92	PLA2G2A (0.38)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL18265982	0.91	L3MBTL1 (0.43)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL23204051	0.91	KDM4E (0.40)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL25775218	0.91	KDM4E (0.40)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
	SCHEMBL25775196	0.91	PLA2G2A (0.43)	PLA2G2APLA2G4AKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.