SCHEMBL1637616

SCHEMBL1637616

CCO[Si](C)(OCC)C(CC)c1ccccc1C(CC)[Si](C)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 1/20 0.35
ESR1 P03372 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TLR8 Q9NR97 1/20 0.32
LTA4H P09960 1/20 0.31
MPO P05164 1/20 0.31
ELANE P08246 1/20 0.30
MAPK1 P28482 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PTPRC P08575 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716567 0.82 LMNA (0.41) ALDH1A1L3MBTL1
SCHEMBL6708538 0.77 KDM4E (0.32) ALDH1A1KDM4EHPGDMAPK1L3MBTL1
SCHEMBL1639304 0.71 TSHR (0.42) TSHRESR1KDM4EMPOCYP1A2
SCHEMBL1639325 0.69 ESR1 (0.31) ESR1
SCHEMBL20658076 0.68 LMNA (0.42) ALDH1A1
SCHEMBL7938711 0.68 TAAR1 (0.38) ALDH1A1MPOCYP1A2CYP2C19
SCHEMBL3450244 0.67 TDP1 (0.39) ALDH1A1TSHRKDM4ETP53SMN1; SMN2
SCHEMBL562866 0.67 TSHR (0.38) ALDH1A1TSHRESR1LTA4HMPO
SCHEMBL19809367 0.67 LMNA (0.45) ALDH1A1TSHRKDM4EHPGDMAPK1
SCHEMBL27957128 0.67 SCN4A (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed