SCHEMBL9716567

SCHEMBL9716567

CCO[Si](C)(OCC)C(CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
POLB P06746 3/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
MIF P14174 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HKDC1 Q2TB90 1/20 0.33
S1PR1 P21453 1/20 0.33
GAA P10253 1/20 0.33
MMP8 P22894 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716576 0.82 LMNA (0.42) LMNAPOLBMEN1KMT2AHTT
SCHEMBL1637616 0.82 ALDH1A1 (0.35) L3MBTL1ALDH1A1
SCHEMBL20658076 0.82 LMNA (0.42) LMNAPOLBMEN1KMT2AHTT
SCHEMBL7938711 0.78 TAAR1 (0.38) LMNAPOLBHTTALDH1A1MAPT
SCHEMBL19809367 0.77 LMNA (0.45) LMNAPOLBMEN1KMT2AHTT
SCHEMBL27957128 0.77 SCN4A (0.39) LMNAPOLB
SCHEMBL12999580 0.74 LMNA (0.42) LMNAPOLBMEN1KMT2AHTT
SCHEMBL19809272 0.74 LMNA (0.42) LMNAPOLBMEN1KMT2AALDH1A1
SCHEMBL523287 0.74 LMNA (0.45) LMNAPOLBMEN1KMT2AMIF
SCHEMBL4494436 0.74 LMNA (0.45) LMNAPOLBMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036202-C Polymerization catalyst MITSUI PETROCHEMICAL IND (JP) 1997-10-22 CN disclosed
CN-1117055-A Polymerization catalyst MITSUI PETROCHEMICAL IND (JP) 1996-02-21 CN disclosed
CN-1030990-C Olefin polymerization process MITSUI PETROCHEMICAL IND (JP) 1996-02-14 CN disclosed
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
CN-88101916-A Olefin polymerization process and catalyst therefor 1988-10-26 CN disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed