SCHEMBL562866

SCHEMBL562866

CCO[Si](OCC)(OCC)C(C)c1ccccc1C(C)[Si](OCC)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
MPO P05164 2/20 0.36
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LTA4H P09960 1/20 0.33
NISCH Q9Y2I1 2/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
NQO1 P15559 1/20 0.32
PTPRC P08575 1/20 0.32
CDC25B P30305 1/20 0.32
ESR1 P03372 1/20 0.31
NLRP3 Q96P20 1/20 0.31
ELANE P08246 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28228273 0.98 TSHR (0.36) TSHRMPOADRA2AADRA2BADRA2C
SCHEMBL1765857 0.87 TSHR (0.53) TSHRMPOALDH1A1NISCHGABRA1
SCHEMBL8087531 0.87 ALDH1A1 (0.44) TSHRMPOADRA2AADRA2BADRA2C
SCHEMBL28332142 0.87 CA1 (0.41) TSHRADRA2AADRA2BADRA2CALDH1A1
SCHEMBL2526800 0.84 SLC6A2 (0.31) TSHRMPOADRA2AADRA2BADRA2C
SCHEMBL2520763 0.84 IDO1 (0.33) TSHRMPOADRA2AADRA2BADRA2C
SCHEMBL3305911 0.82 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL2763038 0.81 ADRA2A (0.33) ADRA2AADRA2BADRA2CALDH1A1NISCH
SCHEMBL574617 0.81 TAAR1 (0.39) ALDH1A1GABRA1GABRB2
SCHEMBL7917080 0.80 ADRA2A (0.33) ADRA2AADRA2BADRA2CALDH1A1NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739670-B1 SOL-GEL DERIVED COMPOSITIONS ABS MAT INC (US) 2023-10-11 EP claimed
US-10881598-B2 Method of using personal and home care compositions containing a sol-gel derived material ABS MATERIALS, INC. (US) 2021-01-05 US claimed
US-10391470-B2 Sol-gel derived compositions ABS MATERIALS, INC. (US) 2019-08-27 US claimed
US-20180360718-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL AQUANEX TECHNOLOGIES, LLC 2018-12-20 US claimed
US-20170028380-A1 SOL-GEL DERIVED COMPOSITIONS AQUANEX TECHNOLOGIES, LLC 2017-02-02 US claimed
US-20160324746-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL BRIGGS, ADAM 2016-11-10 US claimed
US-20160316804-A1 SOL-GEL ENCAPSULATED WATER-SOLUBLE ORGANIC LIQUIDS AND ORGANIC LIQUIDS AND METHOD OF USING SAME AQUANEX TECHNOLOGIES, LLC 2016-11-03 US claimed
US-20160271581-A1 METHOD FOR REMOVING MICROCYSTINS FROM AN AQUEOUS SOLUTION USING PARTICLES HAVING A REACTIVE THIOL FUNCTIONAL GROUP AQUANEX TECHNOLOGIES, LLC 2016-09-22 US claimed
US-9440869-B2 Sol-gel derived compositions ABS MATERIALS, INC. (US) 2016-09-13 US claimed
US-9144784-B2 Sorbent material and method for using the same ABS MATERIALS (US) 2015-09-29 US claimed
US-20110132845-A1 METHOD FOR EXTRACTING A METAL PARTICULATE FROM AN AQUEOUS SOLUTION USING A SOL-GEL DERIVED SORBENT AQUANEX TECHNOLOGIES, LLC 2011-06-09 US claimed
EP-1203032-A4 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INC (US) 2006-06-21 EP claimed
US-20040146766-A1 Proton electrolyte membranes, methods of making proton electrolyte membranes, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION 2004-07-29 US claimed
US-6559197-B2 Coating for siliceous surfaces comprising a hydrolyzable silicon compound such as a trialkoxysilane, halosilane, alkoxysilane and mixtures thereof and a photoacid catalyst; shelf life CORNING INCORPORATED 2003-05-06 US claimed
US-20030045600-A1 Coating for siliceous surfaces comprising a hydrolyzable silicon compound such as a trialkoxysilane, halosilane, alkoxysilane and mixtures thereof and a photoacid catalyst; shelf life CORNING INCORPORATED 2003-03-06 US claimed
JP-2002543039-A 2002-12-17 JP claimed
EP-1203032-A1 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2002-05-08 EP claimed
US-6326416-B1 MIXTURE OF RADIATION CURABLE OLIGOMER AND ADHESION PROMOTER CORNING INCORPORATED 2001-12-04 US claimed
US-6316516-B1 FOR PRODUCING PROTECTIVE COATINGS, FOR ENCAPSULATING OPTICAL FIBERS TO ENHANCE DURABILITY, NON-DELAMINATING CORNING INCORPORATED 2001-11-13 US claimed
WO-2000066636-A1 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2000-11-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10881598-B2 Method of using personal and home care compositions containing a sol-gel derived material FPR3, FPR1, MSN TSHR 1853/4885MPO 1898/4885ADRA2A 1834/4885
US-20160324746-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL FPR3, FPR1, SGMS1 TSHR 1878/4885MPO 2172/4885ADRA2A 1800/4885
US-20180360718-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL FPR3, FPR1, SGMS1 TSHR 1877/4885MPO 1915/4885ADRA2A 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.