SCHEMBL1637634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15498111	0.96	AHR (0.46)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL10122366	0.93	AHR (0.44)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL10122361	0.92	PLA2G2A (0.44)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL23509138	0.90	PLA2G2A (0.43)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL10122363	0.90	PLA2G2A (0.43)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL10122347	0.89	PLA2G2A (0.46)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL1637636	0.88	AHR (0.52)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL9109225	0.88	GABRP (0.54)	AHRALOX5GABRPGABRDGABRA1
	SCHEMBL16477706	0.87	AHR (0.40)	AHRALOX5PLA2G2APLA2G4AHPGD
	SCHEMBL24786944	0.87	MAPT (0.42)	AHRALOX5HPGDCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.