Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CBX7 | O95931 | 2/20 | 0.56 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.56 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201165 | 0.82 | ALDH1A1 (0.65) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL18415222 | 0.81 | RAD52 (1.00) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL25890527 | 0.80 | ALDH1A1 (0.63) | ALDH1A1CBX7CDY1; CDY1BCDYL2CDYL | |
| SCHEMBL16377147 | 0.80 | RAD52 (0.63) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL38659116 | 0.80 | RAD52 (0.59) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL27780991 | 0.79 | ALDH1A1 (0.59) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL2489202 | 0.79 | HTR7 (0.56) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL28449922 | 0.79 | ALDH1A1 (0.81) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL24281187 | 0.77 | RAD52 (0.72) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 | |
| SCHEMBL18189026 | 0.77 | ALDH1A1 (0.67) | RAD52ALDH1A1CBX7CDY1; CDY1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018103-A1 | 3-HYDROXYOXINDOLE DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| US-20230234938-A1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20230234938-A1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018103-A1 | 3-HYDROXYOXINDOLE DERIVATIVES AS CRHR2 ANTAGONIST | CRHR2, CRHR1, CRH | RAD52 2416/4885ALDH1A1 4326/4885CBX7 472/4885 |
| US-20230234938-A1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | PARP1, PARP2, PARP3 | RAD52 240/4885ALDH1A1 426/4885CBX7 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.