SCHEMBL1637769

SCHEMBL1637769

CO[Si](OC)(OC)c1ccccc1-c1cccc([Si](OC)(OC)OC)c1[Si](OC)(OC)OC

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MAP2K7 O14733 1/20 0.30
GMNN O75496 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30
CYP2C19 P33261 1/20 0.30
THPO P40225 1/20 0.30
MTOR P42345 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1109638 0.87 ALDH1A1 (0.37) KDM4EMAP2K7GMNNALDH1A1LMNA
SCHEMBL1109640 0.85 PDCD1 (0.34) KDM4EALDH1A1LMNATP53MAPT
SCHEMBL1639805 0.83 KDM4E (0.31) KDM4EALDH1A1SMN1; SMN2
SCHEMBL1639898 0.76 CYP1A2 (0.30) CYP1A2
SCHEMBL7188378 0.75 ALDH1A1 (0.38) KDM4EALDH1A1LMNATP53MAPT
SCHEMBL13027818 0.75 CYP1A2 (0.33) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL29975082 0.75 ALDH1A1 (0.38) KDM4EALDH1A1LMNATP53MAPT
SCHEMBL332012 0.75 ALDH1A1 (0.41) KDM4EMAP2K7GMNNALDH1A1LMNA
SCHEMBL30264142 0.75 ALDH1A1 (0.41) KDM4EMAP2K7GMNNALDH1A1LMNA
SCHEMBL13027802 0.73 CA1 (0.42) KDM4EALDH1A1LMNATP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed