SCHEMBL1637862

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636395	0.98	ESR1 (0.46)	ESR1ESR2PGRALOX5CA1
	SCHEMBL1636030	0.98	ESR1 (0.46)	ESR1ESR2PGRALOX5CA1
	SCHEMBL1636399	0.96	ESR1 (0.44)	ESR1ESR2PGRALOX5CA1
	SCHEMBL1636944	0.95	ESR1 (0.50)	ESR1ESR2PGRALOX5CA1
	SCHEMBL1636397	0.93	HSD17B1 (0.47)	ESR1ESR2PGRALOX5HSD17B1
	SCHEMBL1636828	0.93	ESR1 (0.47)	ESR1ESR2PGRALOX5CA1
	SCHEMBL1636936	0.93	ESR1 (0.47)	ESR1ESR2PGRALOX5CA1
	SCHEMBL12037403	0.93	ESR1 (0.50)	ESR1ESR2PGRALOX5CA1
	SCHEMBL13979519	0.93	ESR1 (0.50)	ESR1ESR2PGRALOX5CA1
	SCHEMBL1636939	0.91	ESR1 (0.46)	ESR1ESR2PGRALOX5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.